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桥本甲状腺炎(Hashimoto’s thyroiditis,HT)是免疫系统功能紊乱,介导攻击自身组织的免疫反应,临床表现为甲状腺组织肿大或结节,血液检测出TGAb、TPOAb等抗体。甲状腺癌常见病理类型包括:乳头状癌、髓样癌、滤泡癌和未分化癌等,其中以乳头状癌(papillary thyroid carcinoma,PTC)最常见。HT可合并甲状腺癌,其中主要是甲状腺乳头状癌。现就其流行病学、临床与组织病理学特点、发病机制、诊断、治疗及预后等做一论述。
Hashimoto’s thyroiditis (HT) is an immune system dysfunction that mediates the immune response to its own tissues. The clinical manifestations are enlarged or nodular thyroid gland, and antibodies such as TGAb and TPOAb are detected in the blood. Common pathological types of thyroid cancer include papillary carcinoma, medullary carcinoma, follicular carcinoma and undifferentiated carcinoma, among which papillary thyroid carcinoma (PTC) is most common. HT can be combined with thyroid cancer, which is mainly papillary thyroid cancer. Now on its epidemiology, clinical and histopathological features, pathogenesis, diagnosis, treatment and prognosis to do a discussion.