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目的 :研究留置胃管反复洗胃对重度有机磷中毒 (AOPP)患者的治疗及愈后影响。方法 :选择资料完整的重度AOPP患者共 5 0例。按常规洗胃后留管与否分为留置胃管组及非留管组两组。研究两组间中毒至开始抢救时间 ,达阿托品化时间、达阿托品化阿托品量、阿托品总量、CHE恢复正常时间及死亡数、住院时间等项目。结果 :5 0例重度AOPP患者留管组 2 1例 ,占 42 %。未留管组 2 9例 ,占 5 8%。留管组与非留管组达阿托品化时间分别为 ( 4 9± 1 2 )和 ( 6 8± 1 2 )h ;达阿托品化量留管组与非留管组分别为 ( 2 89 3± 187 5 )和 ( 4 49 7± 2 2 3 6)mg ;CHE恢复正常时间留管组与非留管组分别为 ( 15± 4 6)和 ( 18± 5 2 )d。死亡数留管组与非留管组分别为 1例和 9例。上述数据经统计学处理均有显著差异 ( P <0 .0 5 )。结论 :留置胃管反复洗胃可明显减少AOPP患者阿托品化量、缩短达阿托品时间及CHE恢复时间、降低死亡率
Objective: To study the treatment and prognosis of patients with severe organophosphorus poisoning (AOPP) after gastric lavage with repeated gastric lavage. Methods: A total of 50 patients with severe AOPP were selected. According to conventional gastric lavage tube or not into two groups of indwelling gastric tube group and non-tube group. To study the poisoning between the two groups to start the rescue time, dalto esterification time, atropine product atropine, atropine total, CHE recovery time and the number of deaths, hospitalization time and other projects. Results: Fifty-one patients with severe AOPP had 21 cases, accounting for 42%. There were 29 cases in the unmanaged group, accounting for 58%. The time of uptake of atropine was (49 ± 1 2) and (6 8 ± 1 2) h in the left and right sides of the control group, respectively 187 5) and (4 49 7 ± 2 2 3 6) mg, respectively. The CHE recover time was (15 ± 4 6) and (18 ± 5 2) days respectively. The number of death and non-management group were 1 case and 9 cases. The above data were statistically significant differences (P <0. 05). Conclusion: Indwelling gastric tube repeated gastric lavage can significantly reduce the amount of atropine in AOPP patients, shorten the time of dalteparin and CHE recovery time, reduce mortality