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目的探讨血小板减少症患者血清血小板生成素(thrombopoietin,TPO)水平、血小板TPO受体c-mplmRNA基因转录水平与外周血血小板(platelet,PLT)计数、骨髓巨核细胞计数的关系及其临床意义.方法应用夹心酶联免疫吸附法(sandwich-ELISA)测定50例不同病因血小板减少症患者血清TPO水平,
Objective To investigate the relationship between the level of thrombopoietin (TPO), the transcription level of c-mplmRNA of platelet TPO receptor, platelet count (PLT) and the count of bone marrow megakaryocytes in patients with thrombocytopenia and its clinical significance.Methods The serum TPO levels in 50 patients with different etiopathogenic thrombocytopenia were measured by sandwich-ELISA.