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目的:了解西宁地区婴儿肝炎综合征与巨细胞病毒感染的关系。方法:巨细胞病毒用美国stat Fax 2100酶检仪测定,肝功能用奥林巴斯AU640全自动生化分析仪进行测定。结果:巨细胞IgM(CNV-IgM)感染的婴儿肝炎综合征患儿黄疸较重,病程长,肝功有损伤,有一部分患儿预后不好。巨细胞IgM(CMV-IgM)未感染的婴儿肝炎综合征,病程短,肝功能损伤小,愈后好。两组患儿的肝功能有显著性差异(P<0.05)。结论:孕妇在妊娠早期应进行CMV-IgM-IgG的筛查,对预防CMV的垂直感染有十分重要的意义。
Objective: To understand the relationship between infant hepatitis syndrome and cytomegalovirus infection in Xining area. Methods: Cytomegalovirus using the United States stat Fax 2100 enzyme detection instrument, liver function with Olympus AU640 automatic biochemical analyzer was measured. Results: Infants with giant cell IgM (CNV-IgM) infection had severe jaundice, longer duration and impaired liver function. Some patients had poor prognosis. Giant cell IgM (CMV-IgM) uninfected infantile hepatitis syndrome, short course, small damage to liver function, the prognosis is good. The liver function of two groups had significant difference (P <0.05). Conclusion: Pregnant women should be screened for CMV-IgM-IgG in early pregnancy, which is of great significance in preventing vertical infection of CMV.