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Radiation induced bystander effect(RIBE)has been defined as a biological response to radiations resulting in damage to cells that had not themselves been traversed by a track of the ionizing radiations.It has been shown that the transfer of irradiated cell conditioned medium is able to kill cells that are not directly irradiated.But interlaboratory variability in the production of bystander effects using medium transfer protocols is a well known and frustrating problem.Even within the same laboratory,the effect can fail to be manifested.The study conducted by Mothersill et al.showed that serum serotonin levels determine
Radiation induced bystander effect (RIBE) has been defined as a biological response to radiations resulting in damage to cells that had not themselves been traversed by a track of the ionizing radiations. It has been shown that the transfer of irradiated cells conditioned medium is able to kill cells that are not directly irradiated. By inter-laboratory variability in the production of bystander effects using medium transfer protocols is a well known and frustrating problem. Even within the same laboratory, the effect can fail to be manifested. The study conducted by Mothersill et al .showed that serum serotonin levels determine