The observation that a reduction in food intake, or caloric restriction (CR), delays the decline in physiological fitness and extends the life span of organ
Endocrine hormones impact aging and age-related disease.Growth hormone (GH) affects not only somatic growth but also drives aspects of metabolism and stress
The pathogenesis of sporadic Alzheimers disease (AD) is intimately related to brain aging.Thus, the aged brain especially when metabolically manipulated can
Estrogens have been shown to protect brain tissue in a number of acute neuronal compromising conditions as well as in chronic neurodegenerative diseases.The