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广西特色药用植物桂郁金的挥发油、姜黄素类成分及其微量元素的分离研究近年来有了较明显的进展,并发现该药存在多靶点的抗肝纤维化药理学作用。文章从桂郁金的挥发油分离成分、姜黄素类成分研究及其微量元素的分离研究进展,及其抗脂质过氧化,抑制炎症反应,抑制肝星状细胞增殖、诱导凋亡及抑制蛋白分泌,抗凝血和促纤溶等方面所显示的抗肝纤维化药理学作用,对该药的开发研究进展进行综述。
In recent years, the study on the separation of essential oils, curcuminoids and their trace elements from Guangxi medicinal plant Guiyujin has made remarkable progress and found that the drug has multi-target anti-hepatic fibrosis pharmacological effects. In this paper, the volatile oil from Curcuma longissimum composition, curcumin composition and trace elements of its research, and its anti-lipid peroxidation, inhibit inflammatory response, inhibit hepatic stellate cell proliferation, induce apoptosis and inhibit protein secretion , Anti-coagulation and fibrinolysis showed anti-hepatic fibrosis pharmacological effects of the drug development and research are reviewed.