论文部分内容阅读
我们曾分别用6945mg、6350mg 阿托品,成功地抢救了两例重度有机磷中毒患者。根据自己的临床经验,将阿托品的应用分为三期:Ⅰ期:为阿托品药物反应期,Ⅱ期:阿托品化期,Ⅲ期:阿托品中毒期。介绍了各期观察指标及处理方法。报道如下:例一:患者女,28岁。服增效辛硫磷约50ml,一小时后来院就诊。患者深昏迷,流涎,瞳孔极度缩小。皮肤灰白湿冷,肌肉颤动。BP:60/40mmHg,P:102次/分。即刻洗胃,静脉注射阿托品、解磷定。开始剂量为20mg/10′静注,疗效不佳。2.5小时后改为30mg/10′静注。后隔8小时,改为50mg/10′静注。又隔5小时,改为100mg/10′静注。约半小时后,患者抽搐,呼吸停止。即人工呼吸、吸 O_2加用洛贝林、甘露醇
We have successfully treated two patients with severe organophosphate poisoning with 6945mg and 6350mg atropine, respectively. According to their own clinical experience, the application of atropine is divided into three phases: stage I: atropine drug response period, stage II: atropine, stage III: atropine poisoning period. Introduced each period of observation index and processing method. Reported as follows: Example 1: Female patient, 28 years old. Increased efficacy of phoxim about 50ml, one hour later to hospital. Deep coma patients, salivation, pupil extremely narrowed. Skin gray and cold, muscle fibrillation. BP: 60/40 mmHg, P: 102 times / min. Immediate gastric lavage, intravenous atropine, phosphate solution. The initial dose of 20mg / 10 ’intravenous, poor efficacy. 2.5 hours later changed to 30mg / 10 ’intravenous injection. After an interval of 8 hours, changed to 50mg / 10 ’intravenous injection. Another 5 hours, changed to 100mg / 10 ’intravenous injection. About half an hour later, the patient twitches and stops breathing. That artificial respiration, inhalation of O_2 plus Luo Bei Lin, mannitol