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目的探讨异位妊娠(EP)患者临床症状与血β-人绒毛膜促性腺激素(β-hCG)值、包块大小和子宫内膜厚度的关系。方法回顾分析192例经手术及病理证实的异位妊娠患者资料,分析临床症状与血β-hCG值、包块大小及子宫内膜厚度的相关性。结果 192例中,有停经者156例,血β-hCG值中位数为1985.8mIU/ml,高于无停经36例的647.7mIU/ml(P<0.01);有、无停经者的包块大小和子宫内膜厚度均无统计学差异(P>0.05)。有阴道流血者155例,血β-hCG值中位数为1162.0mIU/ml,低于无阴道流血37例的2679.0mIU/ml(P<0.01);前者子宫内膜厚度小于后者(0.80cm vs.0.90cm)(P<0.05);但两者包块大小差异无统计学意义(P>0.05)。有腹痛者(83例)包块大于无腹痛者(109例)(2.35cm vs.2.10cm)(P<0.05)。两者血β-hCG值及子宫内膜厚度均无统计学差异(P>0.05)。结论 EP患者的三大临床症状与血β-hCG值、包块大小及子宫内膜厚度密切相关。
Objective To investigate the clinical symptoms of ectopic pregnancy (EP) patients with β-human chorionic gonadotropin (β-hCG) value, the size of the mass and the relationship between endometrial thickness. Methods The data of 192 patients with ectopic pregnancy confirmed by operation and pathology were retrospectively analyzed. The correlation between clinical symptoms and β-hCG, mass size and endometrial thickness was analyzed. Results Of the 192 patients, 156 had menopause, and the median blood β-hCG value was 1985.8 mIU / ml, which was higher than 647.7 mIU / ml without stopping menopause (P <0.01) There was no significant difference in the size and endometrial thickness (P> 0.05). There were 155 cases of vaginal bleeding, the median blood β-hCG was 1162.0mIU / ml, which was lower than 2679.0mIU / ml in 37 cases without vaginal bleeding (P <0.01); the former was less than the latter vs.0.90cm) (P <0.05). However, there was no significant difference in the size of the mass between the two groups (P> 0.05). Those with abdominal pain (83 cases) had larger mass than those without abdominal pain (109 cases) (2.35 cm vs. 2.10 cm) (P <0.05). Both serum β-hCG and endometrial thickness were no significant difference (P> 0.05). Conclusion The three clinical symptoms of EP patients are closely related to the blood β-hCG value, mass size and endometrial thickness.