论文部分内容阅读
促红细胞生成素是一种促进红系造血前体细胞增殖、分化的细胞因子,主要作用为促进红细胞增殖,应用于临床各种贫血治疗。随着研究进展,学者发现促红细胞生成素为一种多功能营养因子及神经保护因子,具有调节中枢神经系统发育、神经营养及神经保护作用。脑缺血性卒中实验研究显示,促红细胞生成素可有效改善中枢神经系统疾病所致的神经功能缺损,本文主要概述促红细胞生成素在脑缺血性卒中动物模型的研究进展,及其发挥神经保护作用所经由的分子机制。相信随着实验研究进展,其在脑缺血性卒中临床治疗方面将拥有更广阔的前景。
Erythropoietin is a cytokine that promotes the proliferation and differentiation of hematopoietic progenitor cells in erythrocytes. The main function of erythropoietin is to promote the proliferation of erythrocytes and to apply it to various kinds of clinical anemia treatment. With the research progress, scholars have found that erythropoietin is a multifunctional nutritional factor and neuroprotective factor, which has the functions of regulating the development of central nervous system, neurotrophic and neuroprotective. Experimental study of cerebral ischemic stroke shows that erythropoietin can effectively improve the neurological deficits caused by central nervous system diseases. This article mainly summarizes the research progress of erythropoietin in animal model of cerebral ischemic stroke and its function of nerve The molecular mechanism of protection. Believe that with the experimental research progress, its clinical treatment of cerebral ischemic stroke will have a broader perspective.