【摘 要】
：
A series of novel derivatives of indirubin were synthesized and evaluated for their anti-proliferative activity against human cancer cell lines of SGC7901, A549
【机 构】
：
Center of Drug Discovery,Shanghai Sun-sail Pharmaceutical Science & Technology Co.
论文部分内容阅读
A series of novel derivatives of indirubin were synthesized and evaluated for their anti-proliferative activity against human cancer cell lines of SGC7901, A549, HL-60, SK-BR-3 and HCT116. Most of the compounds displayed more potent activity than Sunitinib. In addition, the derivatives showed improved water solubility, which may be favorable to their pharmacokinetic performances.
其他文献
A novel nano-composite of polyaniline/mesoporous carbon(PANI/CMK-3)was prepared with mesoporous carbon(CMK-3)serving as the support.Electrochemical asymmetric c
More than a decade of dedicated experimental work on the collisional physics of protoplanetary dust has brought us to a point at which the growth of dust aggreg
A series of chiral secondary alcohols were easily prepared by means of asymmetric hydrogenation of prochiral aromatic ketones using a new ((Rax)-BuP)/(R,R)-DPEN
The electropolymerized film of amaranth was prepared on the surface of graphite pencil electrode(GPE)using cyclic voltammetric technique.This poly(amaranth)film
An efficient and easy method for one-pot three-component synthesis of l,3-disubstituted-3H-benzo[f]chromenes by the condensation of naphtol,aromatic aldehyde de
Mesoporous carbon(MC)with surface area of 380 m2/g was prepared and employed as the carbon support of Pt catalyst for counter electrode of dye-sensitized solar
The fluorescence staining method and scanning electron microscopy(SEM)were used to study the effect of ozone(O3)inactivating Cryptosporidium in water and cell u
A versatile and effective method for incorporating functional groups on the pore wall of three-dimensionally ordered macroporous cross-linked polystyrene(3DOM C
The fluorination reaction involving a/%ketosulfones by SelectfluorTM was efficiently promoted by the ionic liquid, [Hbim]BF4 (IL) as a reaction medium with meth
Electrocatalytic oxidation of thiosulfate at the 2,7-BFEFMCPE occurs at a potential about 460 mV less positive than that unmodified carbon paste electrode.The d