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目的 :探讨引起真菌性鼻窦炎的致病真菌及与临床的关系 ,为临床医师提供诊断依据 ,指导治疗。方法 :对 10 0例真菌性鼻窦炎患者 ,通过行鼻内窥镜手术所取的窦腔内容物送病理诊断的同时 ,行标本直接涂片镜检 ,接种培养 ,菌种鉴定。结果 :直接镜检霉菌阳性 98例 ;接种培养霉菌阳性 37株 ,其中曲霉菌属 31株 ,包括烟曲霉 14株 ,黄曲霉 10株 ,构巢曲霉 3株 ,灰绿曲霉 1株 ,并发现 3株曲霉新种被分别命名为北京曲霉 ,齐祖同曲霉 ,王端礼曲霉。其它种霉菌有少根根霉 1株 ,尖端足分支菌 3株 ,波氏假性霉样真菌 1株 ,链格孢子菌 1株。结论 :真菌性鼻窦炎的致病真菌以曲霉菌属为主 ,其预后与致病菌种和感染类型有一定关系
Objective: To explore the relationship between pathogenic fungi causing fungal sinusitis and its clinical significance, to provide clinicians with diagnostic evidence and guide treatment. Methods: One hundred and ten patients with fungal sinusitis were treated by nasal endoscopy for sinus pathological diagnosis. At the same time, specimens were directly smeared microscopically, inoculation culture and strain identification. Results: There were 98 positive cases of direct microscopic fungi, 37 were positive for inoculation and culture, of which 31 were Aspergillus, including 14 Aspergillus fumigatus, 10 Aspergillus flavus, 3 Aspergillus nidulans and 1 Aspergillus glaucoma. New strains of Aspergillus were named as Aspergillus kawachii, Qi ancestor, Aspergillus flavus. Other species of mold Rhizopus a Rhizopus, tip mycoplasma 3, Pseudomonas fluorescens 1, Alternaria sp. Conclusion: The pathogenic fungi of fungal sinusitis are mainly Aspergillus, whose prognosis is related to the pathogenic bacteria and infection types