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女子雄性化症状可由于雄激素的产量增加或由于靶器管的敏感性亢进。肾上腺和卵巢的雄激素分泌量,雄激素前驱物质在外围组织中的转变率,和雄激素的代谢清除率都能影响雄激素产量。毛囊和皮脂腺对雄激素的敏感性受靶细胞内5a还原酶的活力控制,后者能将睾酮转变为更强有力的雄激素——二氢睾酮,有人证明多毛症妇女的皮肤标本中,睾酮/二氢睾酮的转换率增加,几乎达到正常男子水平。这些患者血浆睾酮与二氢睾酮水平仅略高于正常,而月经周期不受影响。有人认为多毛症妇女血浆睾酮的一日内波动很大,至少要在一日内抽血4次,每次间隔6小时,才能得出雄激素的平均水平。
Male symptoms of mastitis may be due to increased production of androgens or due to hypersensitivity to the target tube. Androgen secretion in the adrenal and ovaries, the transition rate of androgen precursors in peripheral tissues, and the metabolic clearance of androgens can affect androgen production. The sensitivity of the hair follicles and sebaceous glands to androgens is governed by the activity of the 5a intracellular reductase in target cells, which converts testosterone to the more potent androgen-dihydrotestosterone. It has been shown that testicular / Dihydrotestosterone conversion rate increased, reaching almost normal male level. These patients plasma testosterone and dihydrotestosterone levels were only slightly higher than normal, but the menstrual cycle is not affected. Some people think that hirsutism in women with large fluctuations in plasma testosterone within a day, at least one day, 4 times the blood, every 6 hours interval, in order to reach the average level of androgens.