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本文总结我院从1985年5月～1995年5月共收治浅表性膀胱癌56例,经开放性或TUR-TB术后膀胱腔内灌注丝裂霉素C观察其预防复发的疗效。56例均为O期或A期(TaT_1)肿瘤。病理分级: O级8例,Ⅰ级14例,Ⅰ-Ⅱ20例,I-Ⅱ级9例,IV级5例,均为乳头状移行细胞癌。56例中36例完全有效,占64%;部分有效8例,占15%。总有效率为79%,无效12例,总复发率占21.3%。丝裂霉素C作膀胱内灌注预防浅表性膀胱癌术后复发是一种安全,有效的方法。
This article summarizes our hospital from May 1985 to May 1995 were treated 56 cases of superficial bladder cancer, after open or TUR-TB intravesical instillation of mitomycin C to observe the effect of prevention of recurrence. 56 cases were all O or A (TaT_1) tumors. Pathological grade: O grade in 8 cases, Ⅰ grade in 14 cases, Ⅰ-Ⅱ20 cases, I-Ⅱ grade in 9 cases, IV grade in 5 cases, are papillary transitional cell carcinoma. Of 56 cases, 36 cases were completely effective, accounting for 64%; some were effective in 8 cases, accounting for 15%. The total effective rate was 79%, ineffective in 12 cases, the total recurrence rate was 21.3%. Mitomycin C for intravesical instillation to prevent postoperative recurrence of superficial bladder cancer is a safe and effective method.