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【答】氢化可的松不溶于水,故其针剂为47～55%乙醇溶液;而庆大霉素为硫酸盐,易溶于水,而难溶于有机溶媒.故二者相加则发生沉淀.如将氢化可的松针剂先用5%葡萄糖或生理盐水稀释,这样因有机溶媒——乙醇占比例很小,加入硫酸庆大霉素可防止沉淀发生.经实验证明如此.我院临床上因病情需要,有这样使用的病例.具体做法是将50mg氢化可的松针剂先与500m15%葡萄糖液混合,再加入硫酸庆大霉素溶液滴注,未见异常情况发生.不过,我院此2种药伍用比较多的病例,是将庆大
[A] hydrocortisone is not soluble in water, so the injection of 47 to 55% ethanol solution; and gentamicin sulfate, soluble in water, insoluble in organic solvents, so the two together Such as hydrocortisone injection first diluted with 5% glucose or saline, so that due to organic solvent - ethanol accounted for a small proportion, adding gentamicin sulfate can prevent the precipitation occurred. The experimental results show that our hospital clinical On the condition due to the need to use such cases, the specific practice is to 50mg hydrocortisone injection first mixed with 500m15% glucose solution, then add gentamicin sulfate solution infusion, no abnormalities occurred, but our hospital This 2 kinds of drugs with more cases, will celebrate big