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目的探讨胃癌来源的krukenberg瘤的临床特点、诊断及治疗经验。方法回顾性分析我院1993~2003年共27例胃癌伴卵巢转移的诊治经过及预后。结果本组资料全部为绝经前女必患者。术前诊断率低(15/27),病理分化差,胃原发肿瘤全部侵出浆膜层,经积极治疗,前5年平均生存期8.9个月,后5年平均生存期16.9个月。结论胃癌伴卵巢转移好发于绝经前妇女,恶性程度高,易漏诊、误诊。预后虽差,但遵循个体化原则,新辅助化疗加手术及术后辅助腹腔化疗、静脉化疗,可明显改善预后。
Objective To investigate the clinical features, diagnosis and treatment of krukenberg tumor originated from gastric cancer. Methods A retrospective analysis of our hospital from 1993 to 2003, a total of 27 cases of gastric cancer with ovarian metastasis and prognosis. Results of this group of information for all women must be premenopausal patients. Preoperative diagnosis rate is low (15/27), pathological differentiation is poor, primary gastric cancer invading the serosa, after active treatment, the first 5 years the average survival of 8.9 months, 5 years after the average survival of 16.9 months. Conclusion Gastric cancer with ovarian metastasis predisposes to premenopausal women with high degree of malignancy, misdiagnosis and misdiagnosis. The prognosis is poor, but follow the principle of individualism, neoadjuvant chemotherapy plus surgery and postoperative adjuvant intraperitoneal chemotherapy, intravenous chemotherapy, can significantly improve the prognosis.