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四氯化碳(CCl_4)中毒对机体许多脏器和组织造成损伤,尤以肝脏为甚。我们观察了大鼠CCl_4中毒肝脏钙调素和其他与钙代谢有关酶活性变化,以求探讨CCl_4中毒肝脏损伤的发病机理。
Carbon tetrachloride (CCl_4) poisoning causes damage to many organs and tissues in the body, especially in the liver. We observed changes in hepatic calmodulin and other enzymes related to calcium metabolism in rats with CCl_4 poisoning in order to explore the pathogenesis of hepatic injury induced by CCl_4 poisoning.