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玉米胚芽经提取精制得到粉状物(YF)。以含15％YF的饲料饲喂大、小鼠,可在短期内阻抑实验性高血脂大、小鼠血清总胆固醇(TC)的升高(P<0.01),并显著升高小鼠高密度脂蛋白胆固醇(HDL-C)含量(P<0.01),使TC-HDL-c/HDL-c显著降低(P<0.01)。对高血脂患者食用YF2个月的食疗观察表明,YF的降脂效果与动物实验一致,并且能使血浆卵磷脂酰基转移酶(LCAT)相对活性升高(P<0.05)。提示YF可能具有促进体内游离胆固醇(FC)转化为酯化胆固醇(EC),从而加速胆固醇从肝内移出的作用,对此尚需进一步研究。
Corn germ was refined by extraction powder (YF). Feeding large and small mice with 15% YF feed could inhibit experimental hyperlipidemia and raise the serum total cholesterol (TC) (P <0.01) The content of HDL-C (P <0.01) decreased the level of TC-HDL-c / HDL-c significantly (P <0.01). Dietary observation of patients with hyperlipidemia for 2 months showed that the lipid-lowering effect of YF was consistent with that of animals and the relative activity of plasma lecithin acyltransferase (LCAT) was increased (P <0.05). The results suggest that YF may promote the conversion of free cholesterol (FC) into esterified cholesterol (EC) in the body, so as to accelerate the cholesterol removal from the liver, which needs further study.