论文部分内容阅读
目的 评价他汀类药物单用及与不饱和脂肪酸联用治疗老年混合型高脂血症的疗效与安全性。方法 95例混合型高脂血症患者随机分为四组 :舒降之组、洛伐他汀组、洛伐他汀 +Omega 3组、脂必妥组。治疗 8周 ,观察降脂疗效、不良反应。结果 他汀与不饱和脂肪酸联用类降低甘油三酯 (TG)、升高高密度脂蛋白 (HDL C)优于单用他汀类组 ,降胆固醇 (TC)、低密度脂蛋白 (LDL C)、动脉粥样硬化指数 ,二者无显著性差异。降TC、TG、LDL C三项指标达标率他汀类与不饱和脂肪酸联用高于单用他汀类。结论 建议混合型高脂血症患者采用他汀类药物与不饱和脂肪酸联用治疗效果最好
Objective To evaluate the efficacy and safety of statins alone and in combination with unsaturated fatty acids in the treatment of elderly mixed hyperlipidemia. Methods Ninety-five patients with mixed hyperlipidemia were randomly divided into four groups: Shusheng group, Lovastatin group, Lovastatin + Omega 3 group and Zhizhi group. Treatment for 8 weeks, observed lipid-lowering efficacy, adverse reactions. Results Compared with single statin group, cholesterol lowering (TC), low density lipoprotein (LDL C), high fat density lipoprotein (HDL C) and low triglycerides Atherosclerosis index, no significant difference between the two. Reduce TC, TG, LDL C three indicators of compliance rate of statins and unsaturated fatty acids combined with higher than statin alone. Conclusion It is suggested that patients with mixed hyperlipidemia should be treated with statins and unsaturated fatty acids best