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慢性粒细胞白血病急性变(慢粒急变)并骨髓坏死少见,我院遇1例,报道如下。患者女,31岁。因患慢粒47个月伴高热、骨盆和两侧髋部骨痛难忍1周于1989年5月30日入院。体检:T39.6℃,贫血貌,胸骨有压痛,心肺听诊正常。腹软,肝肋下1cm,脾肋下6cm。骨盆及髋部无压痛,两下肢见散在大小不等圆形肿块(直径1～2cm),边缘清楚,质中,轻度压痛。实验室检查:血Hb68g/L,WBC 35×10~9/L。原粒2％,早幼粒8％,中幼粒9％,晚幼粒34％,杆状核17％,分叶核20％,淋巴8％,中幼红2％,血小板49×10~9/L。胸片示两肺广泛片状或点状浸润。骨盆和两侧髋关节摄片
Acute chronic myeloid leukemia (CML acute) and rare bone marrow necrosis, I met a hospital, reported as follows. Female patient, 31 years old. Because of CML with fever for 47 months, pelvic and bilateral hip pain was unbearable for 1 week on May 30, 1989. Physical examination: T39.6 ℃, anemia appearance, sternal tenderness, cardiopulmonary auscultation normal. Abdomen soft, liver ribs 1cm, spleen ribs 6cm. Pelvis and hip without tenderness, see the two lower extremities ranging in size ranging from circular tumor (diameter 1 ~ 2cm), clear edge, quality, mild tenderness. Laboratory tests: blood Hb68g / L, WBC 35 × 10 ~ 9 / L. 2% protoplasm, 8% promyelocytic, 9% jujube, 34% late promyeloid, 17% rhizome, 20% leaf nucleus, 8% lymphatic, 2% 9 / L. Chest radiographs showed widespread flakes or punctate infiltrates in both lungs. Pelvis and hip radiography on both sides