Effect of X-rays on Expression of Caspase-3 and p53 in EL-4 Cells and Its Biological Implications

• 作 者: GUI-ZHI JU Bo SHEN SHI-LONG SU
• 机 构: DepartmentofRadiationBiology
• 出 处: 生物医学与环境科学：英文版
• 发表日期: 2007年6期
• 关键词: X射线 P53 细胞凋亡 多倍体 X-rays Caspase-3 p53 Apoptosis Polyploid
• 基金项目: This work was supported by a grant from the National Natural Science Foundation of China （No. 30670630）.ACKNOWLEDGEMENTSThe authors thank Mr. Peng-Wu LI for cell culture technique.

Objective To investigate the effect of X-rays on expression of caspase-3 and p53 protein in EL-4 cells and its implications in induction of apoptosis and polyploid cells. Methods Mouse lymphoma cell line (EL-4 cells) was used. Fluorescent staining and flo