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目的：观察乳腺癌护理工作中运用综合护理干预的效果。方法：随机抽取我院接受治疗的乳腺癌患者60例，分成对照组与观察组，对照组采用常规护理干预，观察组在对照组护理基础上采用综合护理干预，对比两组患者护理效果。结果：观察组SAS、SDS评分改善情况明显优于对照组；观察组护理满意率明显优于对照组，具有统计学差异（P＜0.05）。结论：乳腺癌患者护理工作中运用综合护理干预，能够明显改善乳腺癌患者的心理状态，加快患者疾病康复速度，值得临床推广。“,”Objective: To observe the effect of comprehensive nursing intervention in nursing care of breast cancer. Methods: randomly selected in our hospital received the treatment of 60 cases of patients with breast cancer, were divided into control group and observation group, control group received routine nursing intervention, the observation group in the control group care on the basis of the use of comprehensive nursing intervention, compared to two groups effect of patient care. Results: the improvement of SAS and SDS scores in observation group was significantly better than that in control group; the nursing satisfaction rate of observation group was significantly better than that of control group (P < 0.05). Conclusion: the comprehensive nursing intervention can significantly improve the psychological status of patients with breast cancer and accelerate the speed of disease recovery, which is worthy of clinical application.