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目的探讨原发性十二指肠恶性肿瘤的临床表现、病变部位、病理类型及辅助检查方法的选择。方法回顾性分析我院1998年1月~2004年12月确诊的53例原发性十二指肠恶性肿瘤患者的临床及病理资料。结果十二指肠恶性肿瘤患者的临床表现无特异性,可有腹痛、腹胀、黄疸、呕吐以及上消化道出血等,肿瘤好发于十二指肠降部,病理类型以腺癌为主,占90.5%。辅助检查以十二指肠镜检出率最高(95%),其他检查检出率依次为胃肠造影(92%)、胃镜(80%)、CT(76%)和B超(59%),结合上述多种检查可提高诊断率。结论提高原发性十二指肠肿瘤生存率的关键是早期诊断,对上述临床表现不能用常见疾病解释者应提高警惕性,结合十二指肠镜、GI、胃镜、CT、B超等多项辅助检查,达到早期诊断的目的。
Objective To investigate the clinical manifestations, pathological features, pathological types, and methods of auxiliary examination of primary duodenal malignancies. Methods The clinical and pathological data of 53 patients with primary duodenal malignancies diagnosed in our hospital from January 1998 to December 2004 were retrospectively analyzed. Results The clinical manifestations of patients with duodenal malignant tumors were not specific. They may have abdominal pain, abdominal distension, jaundice, vomiting, and upper gastrointestinal bleeding. The tumors occurred in the descending part of the duodenum. The pathological type was mainly adenocarcinoma. Accounting for 90.5%. The highest detection rate of auxiliary examination was duodenal (95%), and the other detection rates were gastrointestinal angiography (92%), gastroscopy (80%), CT (76%), and ultrasound (59%). , Combined with the above checks can improve the diagnostic rate. Conclusion The key to improve the survival rate of primary duodenal tumors is early diagnosis. The interpretation of the above clinical manifestations should not be used to explain the common diseases should be increased vigilance, combined with duodenaloscopy, GI, gastroscopy, CT, B-ultrasound, etc. Auxiliary examination to achieve the purpose of early diagnosis.