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目的探索成都市儿童手足口病感染危险因素,为控制手足口病提供科学依据。方法采用病例对照研究方法,选择成都市2013-05/08县级以上医疗机构确诊的156例手足口病病例和从未被确诊为手足口病或疱疹性咽峡炎的195名无发热、出疹症状的儿童,制定统一调查问卷,进行电话调查,采用单因素卡方检验和非条件logistic多元回归分析。结果居住地为农村(OR=1.88,95%CI:1.11,3.18)、无幼儿专用饮水杯(OR=2.49,95%CI:1.11,5.63)、喜欢啃玩具和吃手(OR=2.05,95%CI:1.24,3.41)、发病前7 d接触过患者(OR=10.78,95%CI:3.68,31.56)或周围有病例存在(OR=3.30,95%CI:1.64,6.65)和儿童娱乐场所暴露史(OR=1.93,95%CI:1.09,3.42)为危险因素;接种过轮状疫苗(OR=0.36,95%CI:0.17,0.77)为保护因素。结论幼儿良好的卫生环境和卫生行为、减少与手足口病患儿接触机会、手足口病患儿的有效管理和健康教育、有效落实儿童娱乐场所的消毒工作是预防手足口病的重要措施。
Objective To explore the risk factors of hand, foot and mouth disease in children in Chengdu and to provide a scientific basis for the control of hand foot and mouth disease. Methods A case-control study was conducted in which 156 cases of hand-foot-mouth disease diagnosed in Chengdu medical institutions at county level and above in 2013-05 / 08 and 195 without fever or hand-foot-and-mouth disease Children with rash symptoms, the development of a unified questionnaire, telephone survey, using univariate chi-square test and non-conditional logistic multiple regression analysis. (OR = 2.49, 95% CI: 1.11, 5.63), preferring to eat toys and eat their hands (OR = 2.05, 95% CI: 1.11, 3.18) % CI: 1.24,3.41). There were cases (OR = 3.30, 95% CI: 1.64,6.65) and children’s entertainment places (OR = 10.78,95% CI: 3.68,31.56) Exposure history (OR = 1.93, 95% CI: 1.09, 3.42) was a risk factor. Vaccination with round vaccine (OR = 0.36, 95% CI: 0.17, 0.77) was a protective factor. Conclusion It is an important measure to prevent hand-foot-mouth disease in children with effective sanitation and hygiene, reducing the chance of contact with children with hand-foot-mouth disease, effective management of children with hand-foot-mouth disease and health education.