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已经妊娠的妇女,在必要的情况下,如何使妊娠安全中止,这是计划生育工作中的一个课题。自从妊娠早期采用负压吸引进行人工流产得到了推广以后,研究妊娠中期(即妊娠4—7个月之间)引产的方法,就成为人工流产的主要问题。妊娠4个月以后中止妊娠比妊娠早期人工流产困难得多,国内外曾研究过多种引产方法,均因引产时间过长,增加了感染、流血的机会,个别甚至有造成死亡者。引产困难者最后只好作剖腹取胎，增加孕妇的痛苦。因此研究一种有效的中期妊娠引产药物，受到国内外普遍重视。我校1974年研究试制前列腺素E_2成功，1975年在动物实验基础上，交由妇产科试用于临床。从1975年5月至1976年12月用PGE:羊膜腔外注射，引产110例，除1例外，全部获得成功。平均引、流产时间为15小时52分，副反应轻。以后又将此药物扩大试用范围至市、县、公社卫生院(如长春市产院、市立医院、208陆军医院、四平妇婴医院、榆树县医院、凤祥公社卫生院等)，也得到种成功了良好的效果，受到群众好评。实践证明，前列腺素E_2是一率高，产程短，既安全，又简便的引产药物。现在，妇产科同志们正在进一步改进前列腺素E_2的剂型，以提高其疗效和降低用药量，并通过不断的科学实验，拟在计划生育领域中，多方面应用，为实现“人类要控制自己
Pregnant women, if necessary, how to suspend the safety of pregnancy, which is a task in family planning. Since the introduction of negative pressure during the first trimester of pregnancy induced abortion has been promoted, the study of mid-pregnancy (ie, gestational 4-7 months) induction of labor has become the main problem of induced abortion. Abortion in pregnancy after 4 months of pregnancy is much more difficult than that of abortion in early pregnancy. Many kinds of labor induction methods have been studied both at home and abroad. Both of them have prolonged the time of induction of labor and increased the chances of infection and bloodshed. Some even cause death. Indi-labor who finally had to take cesarean section fetus, increase the pain of pregnant women. Therefore, the study of an effective midwifery induction of labor drugs, widespread attention at home and abroad. Our school in 1974 to study prostaglandin E_2 success, in 1975 on the basis of animal experiments, gynecological trial by the clinical trial. From May 1975 to December 1976 with PGE: amniotic fluid injection, induction of labor in 110 cases, with 1 exception, all were successful. The average lead time for abortion is 15 hours 52 minutes, side effects light. In the future, the drug will be expanded to include city, county and commune hospitals (such as Changchun Municipal Hospital, Municipal Hospital, 208 Army Hospital, Siping Maternal and Child Hospital, Yushu County Hospital, Fengxiang Commune Hospital, etc.) The success of the good results, praised by the masses. Practice has proved that prostaglandin E_2 is a high rate of labor short, safe and easy induction of labor drugs. At present, gynecologists and gynecologists are further improving the dosage form of prostaglandin E_2 to improve its curative effect and reduce the dosage. Through continuous scientific experiments, it is proposed that it should be applied in many fields in the field of family planning. In order to realize the goal of "