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目的分析我院心血管疾病患者非甾体类抗炎药(NSAIDs)应用情况。方法选取2013年1月—2014年5月成都医学院第一附属医院收治的心血管疾病患者506例。回顾性分析NSAIDs的品种、限定日剂量(DDD)。结果 NSAIDs中常用的有对乙酰氨基酚栓、醋氯芬酸肠溶片、肠溶型阿司匹林,分别占21.0%、20.5%、10.5%;506例患者使用NSAIDs后出现不同程度的心血管不良事件55例(10.87%)。结论心血管疾病患者使用NSAIDs时应尽量选择非环氧合酶(COX)抑制剂,并严格评估患者的治疗获益与心血管事件的发生风险,合理选择NSAIDs进行治疗,并加强用药监测,避免不良事件的发生。
Objective To analyze the application of non-steroidal anti-inflammatory drugs (NSAIDs) in patients with cardiovascular diseases in our hospital. Methods 506 patients with cardiovascular diseases admitted to the First Affiliated Hospital of Chengdu Medical College from January 2013 to May 2014 were selected. Retrospective analysis of the varieties of NSAIDs, limiting the daily dose (DDD). Results Acetaminophen suppositories, aceclofenac enteric-coated tablets and enteric-coated aspirin were commonly used in NSAIDs, accounting for 21.0%, 20.5% and 10.5%, respectively. There were 506 patients with varying degrees of cardiovascular adverse events after using NSAIDs 55 cases (10.87%). Conclusions NSAIDs should be used as a non-cyclooxygenase (COX) inhibitor in patients with cardiovascular disease. Strict evaluation of patients’ benefit of treatment and risk of cardiovascular events should be made. NSAIDs should be selected appropriately for treatment and medication monitoring should be strengthened to avoid The occurrence of adverse events.