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以IL-2及IFN-γ等细胞因子转基因的肿瘤细胞接种荷瘤动物,可有效诱导抑制局部及转移肿瘤的特异性免疫反应。为确定IL-2与IFN-γ共表达是否对胰腺癌的免疫反应产生协同作用,将IL-2与IFN-γ基因片段分别克隆至
By inoculating tumor-bearing animals with cytokines such as IL-2 and IFN-γ, tumor-bearing animals can effectively induce local and metastatic tumor-specific immune responses. To determine whether coexpression of IL-2 and IFN-γ is synergistic in the immune response to pancreatic cancer, the IL-2 and IFN-γ gene fragments were cloned into