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目的了解长沙某哨点医院住院严重急性呼吸道感染(SARI)病例流行病学特征、临床表现等,为呼吸道感染疾病的防控和诊疗提供依据。方法收集SARI病例咽拭子标本,相关临床表现资料,采用多重PCR快速检测试剂盒检测流感病毒(Flu)、合胞病毒(RSV)、副流感病毒(PIV)、人鼻病毒(HRV)、人偏肺病毒(HMPV)、腺病毒(Ad V)、博卡病毒(HBo V)、人冠状病毒(Co V),分析病例的临床特征、呼吸道病毒流行病学特征。结果儿科、呼吸科、重症监护室共监测534例SARI病例,呼吸道病毒阳性率为39.13%,检出210株病毒有Flu、RSV、PIV、HRV、HMPV、Ad V、HBo V、Co VO,最多为RSV病毒。男性患者病毒阳性率与女性比较差异有统计学意义(χ2=55.87,P<0.05),小于3岁组病毒阳性率最高(χ2=34.2,P<0.05)。结论 SARI病例监测有利于呼吸道感染疾病的防控和临床诊疗。
Objective To understand the epidemiological characteristics and clinical manifestations of hospitalized severe acute respiratory infections (SARI) in a sentinel hospital in Changsha, and to provide basis for the prevention, treatment and treatment of respiratory tract infections. Methods Samples of throat swabs from SARI patients and related clinical manifestations were collected. Flu virus, syncytial virus (RSV), parainfluenza virus (PIV), human rhinovirus (HRV), human Pneumovirus (HMPV), AdV, HBoV, CoV, the clinical features of the analyzed cases and the epidemiological characteristics of respiratory viruses. Results A total of 534 cases of SARI were detected in pediatric, respiratory and intensive care units. The positive rate of respiratory viruses was 39.13%. Flu, RSV, PIV, HRV, HMPV, Ad V, HBo V and Co VO RSV virus. The positive rate of virus in male patients was statistically different from that in female (χ2 = 55.87, P <0.05). The positive rate of virus in patients younger than 3 years was the highest (χ2 = 34.2, P <0.05). Conclusion SARI surveillance is beneficial to the prevention and control of respiratory tract infections and clinical diagnosis and treatment.