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目的:总结深低温低流量灌注结合中深度血液稀释的体外循环方法在200例婴幼儿法乐四联症的临床应用效果。方法:鼻咽温降至17~20℃(平均18.89±2.56℃),动脉灌注流量20~50ml·kg-1/min(平均37.6±13.0ml·kg-1/min),稀释后血红蛋白44~110g/L(平均68.7±12.6g/L)。结果:采用此种体外循环方法,术后肺部并发症明显降低,术后早期死亡率由10.2%降至3.5%。结论:此种体外循环方法,适用于婴幼儿紫绀型心血管病手术,术后并发症少,临床效果满意,可在临床推广。
OBJECTIVE: To summarize the clinical application of deep hypothermia, low perfusion combined with deep hemodilution cardiopulmonary bypass in the treatment of tetralogy of Fallot in 200 infants. Methods: Nasopharyngeal temperature was decreased to 17 ~ 20 ℃ (mean 18.89 ± 2.56 ℃), arterial perfusion rate was 20 ~ 50ml · kg-1 / min (mean 37.6 ± 13.0ml · kg-1 / min ), And hemoglobin 44-110 g / L (average 68.7 ± 12.6 g / L) after dilution. Results: With this method of extracorporeal circulation, postoperative pulmonary complications were significantly reduced, and the early postoperative mortality rate dropped from 10.2% to 3.5%. Conclusion: This cardiopulmonary bypass method is suitable for cyanotic cardiovascular diseases in infants and young children. The postoperative complications are few and the clinical effect is satisfactory. It can be used clinically.