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美《医学论坛报》第22卷第19期(1981年)报道加利福尼亚州欧文消息:加利福尼亚大学的一研究小组称,孕妇或产后的妇女发生感染时所需要的抗菌素量可能比标准剂量略高。妇产科的副教授米勒(David Miller)说,在斯堪的纳维亚所进行的研究工作提示,氨卡青霉素的半寿期在孕妇服用时减少50％。他们的研究包括产后头几天的病人,她们的生理现象与妊娠很相似。米勒的研究组发现,17名用Cephalosporin Ceforanide治疗产后感染的病人需要较对照组高33％的剂量才能达到同样的血清水平。
The United States Medical Tribune Vol. 22, No. 19 (1981) Irvine, California: A team of researchers at the University of California said that the amount of antibiotics required for a pregnant or postpartum woman may be slightly higher than the standard dose. David Miller, an associate professor of obstetrics and gynecology, said research carried out in Scandinavia suggests that the half-life of ampicillin is reduced by 50% when taken by pregnant women. Their study included patients in the first days of life who were physically similar to their pregnant counterparts. Miller’s team found that 17 patients treated with Cephalosporin Ceforanide for postpartum infection required a 33% higher dose than the control to achieve the same serum levels.