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目的调查2011—2014年冀中能源峰峰集团有限公司总医院儿科住院抗菌药物处方不合理用药的情况,为促进临床合理应用抗菌药物提供依据。方法抽取2011年—2014年冀中能源峰峰集团有限公司总医院儿科住院抗菌药物处方10 000张,对不合理用药情况进行回顾性分析。结果不合理抗菌用药处方1 037张,占抗菌药物处方总数的10.37%;儿科住院抗菌药物处方不合理用药情况主要体现在疗程不当、给药频次不合理以及溶媒选择不当,分别占不合理用药处方的23.82%、21.31%、17.74%;头孢类和青霉素类应用较多,而不合理用药处方率仅为7.20%、6.04%;应用较少的大环内酯类、碳青霉烯类等不合理用药处方率较高,分别为21.65%、18.97%;并且联合用药品种数越多,不合理用药的发生率就越高。结论冀中能源峰峰集团有限公司总医院儿科住院患者抗菌药物应用基本合理,但仍存在诸多不合理用药现象,需进一步加强管理和处方点评力度。
Objective To investigate the unreasonable use of antibacterial drugs for pediatric inpatient department in Jizhong Energy Fengfeng Group Co., Ltd. from 2011 to 2014, and to provide basis for clinical application of antibacterial drugs. Methods A total of 10 000 prescriptions for pediatric inpatient antimicrobials were collected from Jizhong Energy Fengfeng Group Co., Ltd. from 2011 to 2014. Retrospective analysis was conducted on irrational drug use. The results of unreasonable antibacterial drug prescription 1 037, accounting for 10.37% of the total number of antibacterial drugs; pediatric inpatient antimicrobial drugs irrational prescription medication mainly reflected in the improper treatment, frequency of administration is unreasonable and improper selection of solvents, accounting for irrational drug prescriptions 23.82%, 21.31% and 17.74% respectively. The cephalosporins and penicillins were more used, while the unreasonable prescription rates were only 7.20% and 6.04%. The less macrolides and carbapenems The rational prescription rate was higher, accounting for 21.65% and 18.97%, respectively; and the higher the number of combination drugs, the higher the incidence of irrational drug use. Conclusion The application of antibacterials in pediatric inpatients in Jifeng Energy Fengfeng Group Co., Ltd. is basically reasonable. However, there are still many irrational drug use phenomena, and management and prescription reviews need to be further strengthened.