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最近,英国的Hanley等发现,在哺乳动物交感神经系统中,广泛分布着一种有加压素(VP)生物活性和免疫反应性的类加压素多肽(VLP),它存在于神经节的去甲肾上腺素(NE)神经元中,也存在于这些神经纤维支配的组织中。应用精氨酸加压素(AVP)的高特异抗血清测出,腹腔神经节中VLP含量只有颈上神经节的1/4,提示VLP在交感链内的水平可能同VIP一样,也有头端高于尾端的差异。在垂体不能分泌AVP的Brattleboro大鼠的颈上神经节也发现VP样免疫反应性,说明这种VP不是垂体分泌的VP。
Recently, Hanley et al. Found in the UK that a vasopressin polypeptide (VLP) having biologic activity and immunoreactivity of vasopressin (VP) is widely distributed in mammalian sympathetic nervous system and is present in the ganglion Norepinephrine (NE) neurons are also present in the tissues dominated by these nerve fibers. Application of arginine vasopressin (AVP) of the high specific antiserum found in the celiac ganglion VLP content of only 1/4 of the superior cervical ganglion, suggesting that the level of VLP in the sympathetic chain may be the same as VIP, but also the first Higher than the tail of the difference. VP-like immunoreactivity was also found in the superior cervical ganglia of Brattleboro rats that can not secrete AVP in the pituitary, indicating that this VP is not a pituitary-secreting VP.