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小牛血清去蛋白药物能够促进缺氧细胞对氧与葡萄糖的摄取和利用，改善外周及脑部的血液循环障碍和营养失调，促进烧伤创伤愈合，调节中枢神经系统等诸多药理药效。单磷酸腺苷（AM P）为该药物的活性成份之一，构建了以β‐环糊精（β‐CD ）修饰的硫化锌量子点为能量供体，3‐羟基黄酮为能量受体的能量共振转移荧光探针。研究发现A M P能够引起该探针在526 nm处的荧光发射峰强度的猝灭，并且A M P的浓度与探针的荧光强度的Stern‐Volmer曲线呈现良好的线性关系，线性相关系数为0.996，该探针能够应用于药品中AM P的检测。“,”The biological drug of the calf‐blood dialysate has various pharmacological effects .It can promote the oxygen and glu‐cose uptake for the hypoxia cells ,and has beneficial effects on the malfunction of the blood circulation and trophic disturbances in the brain ,and the impairment of peripheral blood circulation .Furthermore ,it is favorable to wound healing and can regulate the central nervous system .Adenosine monophosphate (AM P) is a main active ingredient of the biological drug .In this report ,a fluorescence resonance energy transfer (FRET ) sensor has been developed with β‐CD‐capped ZnS QDs as energy donor and 3‐hydroxyflavone (3‐HF) as energy acceptor .The results showed that AMP can lead to the fluorescence quenching of the FRET sensor at 526 nm ,and the Stern‐Volmer curve between the fluorescence quenching and the concentrations of AMP present a sat‐isfactory linearity with the correlation coefficient of 0.996 .The developed sensor has successfully applied for determination of the AM P in the biological drug .