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目的:研究钩藤对癫癇发作的影响。方法:采用脑电图描记术,观察钩藤对毛果芸香碱致癇家兔大脑皮层放电的影响。结果:腹腔注射钩藤后可使癫(?)发作次数及发作持续时间显著减少,发作间隔时间显著延长(P<0.05)。结论:钩藤注射液能明显抑制癫痫模型电活动,提示钩藤具有抗癇作用。
Objective: To study the effect of Uncaria on seizures. Methods: Electroencephalography was used to observe the effects of Uncaria on the discharge of cerebral cortex in epileptic rabbits induced by pilocarpine. RESULTS: After intraperitoneal injection of Uncaria rhynchophylla, seizure frequency and duration of seizures were significantly reduced, and seizure intervals were significantly prolonged (P<0.05). Conclusion: Uncaria injection can obviously inhibit the electrical activity of epilepsy model, suggesting that Uncaria has anti-epilepsy effect.