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糖尿病肾病(DN)是糖尿病最常见的慢性并发症,是慢性肾功能衰竭的主要原因之一,致残率高,严重威胁着人类的健康。大量流行病学资料和临床研究发现,严格控制血糖可减少及延缓DN的发生、发展。因此,持续高血糖在DN发病机制中具有肯定的作用。但高血糖导致DN的...
Diabetic nephropathy (DN) is the most common chronic complication of diabetes mellitus. It is one of the main causes of chronic renal failure. It has a high morbidity and serious threat to human health. A large number of epidemiological data and clinical studies found that strict control of blood glucose can reduce and delay the occurrence of DN, development. Therefore, persistent hyperglycemia has a positive effect in the pathogenesis of DN. But hyperglycemia leads to DN ...