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目的:观察糖脉康颗粒联合氯沙坦治疗2型糖尿病并发高血压的临床疗效。方法:将120例2型糖尿病并发高血压患者随机平均分为观察组与对照组,观察两组治疗前后各项相关指标的变化及临床总体疗效。结果:治疗12周后,观察组的总有效率为91.7%,显著优于对照组的60.0%(P<0.05),观察组患者的空腹和餐后血糖、糖化血红蛋白与治疗前的差值分别为(1.02±0.99)mmol/L,(2.76±1.28)mmol/L,(0.62±0.23)%,收缩压与舒张压分别为(136.58±9.88)mmHg和(82.25±6.66)mmHg,对照组与之相应的值分别为(0.14±1.15)mmol/L,(0.52±1.19)mmol/L,(0.22±0.17)%,(152.20±7.75)mmHg和(92.85±5.68)mmHg,观察组改善程度均优于对照组(P<0.05)。结论:糖脉康颗粒联合应用氯沙坦,对2型糖尿病并发高血压患者的空腹血糖、餐后血糖、糖化血红蛋白值的控制效果要优于单纯应用氯沙坦,治疗后患者的临床症状显著改善,总体疗效显著优于单纯应用氯沙坦。
Objective: To observe the clinical efficacy of Tang Maikang granule combined with losartan in the treatment of type 2 diabetes complicated with hypertension. Methods: A total of 120 patients with type 2 diabetes mellitus complicated with hypertension were randomly divided into observation group and control group. The changes of the related indexes before and after treatment and the overall clinical effect were observed. Results: After 12 weeks of treatment, the total effective rate in the observation group was 91.7%, which was significantly better than that in the control group (60.0%, P <0.05). The fasting and postprandial blood glucose, glycosylated hemoglobin and the difference before treatment in the observation group were (1.62 ± 1.28) mmol / L and (0.62 ± 0.23)% respectively, and the systolic and diastolic pressures were (136.58 ± 9.88) mmHg and (82.25 ± 6.66) mmHg, respectively (0.22 ± 0.17)%, (152.20 ± 7.75) mmHg and (92.85 ± 5.68) mmHg in the observation group were significantly higher than those in the observation group (0.14 ± 1.15 mmol / L, Better than the control group (P <0.05). Conclusion: Tangmaikang granule combined with losartan can control fasting blood glucose, postprandial blood glucose and glycosylated hemoglobin in patients with type 2 diabetes mellitus complicated with hypertension better than losartan. The clinical symptoms of patients after treatment Improve overall efficacy significantly better than losartan alone.