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目的:探讨骨原发性淋巴瘤的临床特点及治疗方法,以提高诊治水平。方法:回顾性分析12例骨原发性淋巴瘤患者的临床资料,对其临床特点、治疗方法及疗效进行总结。结果:随访1~10年(平均4.2年),采用化、放疗联合治疗的7例患者,6例存活,1例死于多发转移;单纯接受化疗的5例患者,1例死于化疗相关并发症。结论:骨原发性淋巴瘤可结合影像学及病理学等检查早期诊断,对化疗及放疗均敏感,化、放疗联合治疗患者预后效果良好。
Objective: To investigate the clinical features and treatment of primary bone lymphoma in order to improve the diagnosis and treatment. Methods: The clinical data of 12 patients with primary bone lymphoma were retrospectively analyzed. The clinical features, treatment methods and therapeutic effects were summarized. Results: Followed up for 1 to 10 years (mean 4.2 years), 7 patients were treated with combination of chemotherapy and radiotherapy, 6 patients survived and 1 patient died of multiple metastases; 5 patients who received chemotherapy alone and 1 patient died of chemotherapy-related complications disease. Conclusion: Bone primary lymphoma can be combined with imaging and pathology examination of early diagnosis, are sensitive to chemotherapy and radiotherapy, chemotherapy and radiotherapy combined treatment of patients with good prognosis.