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目的观察联合美沙拉嗪颗粒和双歧三联活菌片治疗溃疡性结肠炎的临床疗效。方法选择62例轻、中度结肠炎患者,随机分为治疗组32例,对照组30例。两组均口服美沙拉嗪颗粒1 g,4次/d,疗程8周,治疗组同时加服双歧三联活菌片4片,3次/d。结果治疗组完全缓解25例,有效7例,无效0例;对照组完全缓解14例,有效16例。两组相比,差异有统计学意义(P<0.05)。结论联合应用美沙拉嗪颗粒和双歧三联活菌片具有更好的临床疗效。
Objective To observe the clinical efficacy of combined mesalazine granules and bifidobacterium triple viable tablet in the treatment of ulcerative colitis. Methods Sixty-two patients with mild to moderate colitis were randomly divided into treatment group (n = 32) and control group (n = 30). The two groups were given mesalazine particles 1 g, 4 times / d, the course of treatment for 8 weeks, the treatment group also served with bifid triple live viable tablets 4, 3 times / d. Results In the treatment group, 25 cases were completely relieved, 7 cases were effective and 0 was ineffective. In the control group, 14 cases were completely relieved and 16 cases were effective. The difference between the two groups was statistically significant (P <0.05). Conclusion Combined application of mesalazine granules and bifid triple triple active tablets has better clinical efficacy.