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高凝状态导致肾小球疾病发生、发展。目前检测血液高凝状态的方法较多,但多数较复杂,本文采用西德Hellige厂生产的TEG-D型血栓弹力图仪,以全血复钙法对54例肾脏病进行血液流变学研究。54例分三个实验组:(1)肾病综合征(NS)组,19例(男12、女7),平均年龄24.6岁,有2例伴发静脉栓塞;(2)慢性肾炎(CGN)组,共11例(男8、女3),平均年龄31岁,肾功能正常期;(3)慢性肾功能衰竭(CRF)组,共24例(男18、女6),平均年龄38岁。对照组28例(男17、女11),平均年龄36岁,均无心、肝、肾出血性疾病史。结果:NS组、CRF组、和CGN组r、K、ma、mε与对照组相比差异均有显著意义(P<0.05～0.01),三组m值均无统计学意义(P
Hypercoagulable state led to the occurrence and development of glomerular diseases. At present, there are many ways to detect hypercoagulable state of blood, but most of them are complicated. In this paper, TEG-D thrombelastography instrument produced by Hellige plant in West Germany was used to study the hemorheology of 54 cases of nephropathy . Fifty-four patients were divided into three groups: (1) nephrotic syndrome group (NS), 19 (male 12 and female 7), with a mean age of 24.6 years and 2 patients with venous thromboembolism; (2) chronic nephritis Group, a total of 11 cases (male 8, female 3), average age 31 years old, normal renal function; (3) chronic renal failure (CRF) group, a total of 24 cases (18 males and 6 females) . Control group, 28 cases (17 males and 11 females), mean age 36 years, no heart, liver, kidney bleeding history. Results: There were significant differences in r, K, ma and mε between NS group, CRF group and CGN group compared with control group (P <0.05-0.01), and there was no significant difference between the three groups (P