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结核性腹膜炎是腹水的常见原因之一,临床上切盼有高敏感高特异而简单的筛检方法。腺苷脱氨酶(ADA)是嘌呤碱分解酶,将腺苷分解转化为肌苷,其活性在T淋巴细胞中较B淋巴细胞中更强,并与T细胞分化程度成反比。ADA值的增高取决于T细胞对分枝杆菌抗原的细胞介导免疫反应的成熟状态及其受刺激的程度。ADA测定在诊断结核性胸膜心包腔积液及结核性脑膜炎的价值早已肯定,本研究以测定ADA来评价其在诊断结核性腹水中的作用。作者测定了49例病人腹水ADA值,49例分为三级:A组19例,经腹腔镜、病理或细菌检查证实为结核性腹水;B组20例。病理或超声波检查证实为肝硬化(3例为酒精性肝硬化,17例为肝炎后肝硬化);C组10例,腹水细胞学检查证实为恶性腹水。结果,结核性腹水、肝硬化腹水和恶性腹水三组测
Tuberculous peritonitis is one of the common causes of ascites, clinical look forward to highly sensitive and specific and simple screening method. Adenosine deaminase (ADA) is a purine caustic that converts adenosine to forminosine and its activity is stronger in T lymphocytes than in B lymphocytes and inversely proportional to the degree of T cell differentiation. The increase in ADA value depends on the maturation status of the cell-mediated immune response of T cells to mycobacterial antigens and the extent of their stimulation. The value of ADA determination in the diagnosis of tuberculous pleural effusion and tuberculous meningitis has long been confirmed in this study to determine the role of ADA in the diagnosis of tuberculous ascites. The authors measured 49 patients with ascites ADA value, 49 cases were divided into three: 19 cases in group A, laparoscopic, pathological or bacterial examination confirmed tuberculous ascites; B group of 20 cases. Pathology or ultrasound confirmed liver cirrhosis (3 cases of alcoholic cirrhosis, 17 cases of hepatitis cirrhosis); C group of 10 cases, ascites cytology confirmed as malignant ascites. Results, tuberculous ascites, ascites cirrhosis and malignant ascites three groups