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目的观察经尿道膀胱肿瘤二次电切术治疗膀胱癌的复发与预后情况。方法 86例膀胱癌患者,按随机数字表法分为对照组与观察组,各43例。两组患者均接受经尿道膀胱肿瘤电切术治疗,对照组于首次手术后给予膀胱灌注化疗;观察组于首次手术4周后再次接受电切术治疗,术后给予膀胱灌注化疗。随访12个月,记录两组患者肿瘤复发与预后情况。结果观察组患者肿瘤总体复发率为23.3%,低于对照组的51.2%,差异有统计学意义(P<0.05);两组肿瘤复发病例均给予接受经尿道膀胱肿瘤电切术与膀胱灌注化疗,1年后,观察组无死亡病例,存活率为100.0%,对照组存活率为83.7%,两组比较差异有统计学意义(P<0.05)。结论经尿道膀胱肿瘤二次电切术治疗膀胱癌能有效降低肿瘤复发风险,提高远期存活率,值得推广。
Objective To observe the effect of transurethral resection of bladder tumor on the recurrence and prognosis of bladder cancer. Methods Totally 86 bladder cancer patients were divided into control group and observation group according to random number table method, with 43 cases in each group. Both groups received transurethral resection of the bladder tumor. The control group received intravesical chemotherapy after the first operation. The observation group received transurethral resection 4 weeks after the first operation and intravesical chemotherapy after the operation. The patients were followed up for 12 months and the recurrence and prognosis of the two groups were recorded. Results The overall tumor recurrence rate was 23.3% in the observation group, which was lower than 51.2% in the control group (P <0.05). The tumor recurrence in both groups were treated by transurethral resection of bladder tumor and intravesical chemotherapy One year later, there were no deaths in the observation group. The survival rate was 100.0% in the observation group and 83.7% in the control group. There was significant difference between the two groups (P <0.05). Conclusion Transurethral resection of the bladder tumor for the treatment of bladder cancer can effectively reduce the risk of tumor recurrence and improve the long-term survival rate, it is worth promoting.