论文部分内容阅读
目的观察桂枝芍药知母加味汤联合常规疗法治疗类风湿关节炎的临床疗效。方法将91例类风湿关节炎患者随机分为治疗组(46例)与对照组(45例)。对照组采用常规疗法治疗,治疗组同时加用桂枝芍药知母加味汤。两组疗程均为4周,观察临床疗效及同型半胱氨酸(Hcy)、血沉(ESR)、C反应蛋白(CRP)的变化情况。结果 1治疗组、对照组总有效率分别为89.13%和73.33%;组间临床疗效比较,差异有统计学意义(P<0.05)。2治疗前后组内比较,两组Hcy、CRP、ESR水平差异均有统计学意义(P<0.05);组间治疗后比较,Hcy、CRP、ESR水平及其变化差值差异有统计学意义,治疗组优于对照组(P<0.05)。结论桂枝芍药知母加味汤联合常规疗法治疗类风湿关节炎的疗效满意,可显著缓解患者的临床症状,同时还可改善其高同型半胱氨酸血症,从而可能延缓类风湿关节炎所致心血管进一步损害的进程。
Objective To observe the clinical efficacy of Guizhi Shaoyao Zhimu Decoction combined with conventional therapy in the treatment of rheumatoid arthritis. Methods Ninety-one patients with rheumatoid arthritis were randomly divided into treatment group (n = 46) and control group (n = 45). Control group using conventional therapy, the treatment group also added Guizhi Shaoyao Zhimu Jia Tang. The course of treatment was 4 weeks. The clinical curative effect and changes of Hcy, ESR and CRP were observed. Results 1 The total effective rates of the treatment group and the control group were 89.13% and 73.33% respectively. There was significant difference between the two groups in clinical efficacy (P <0.05). There were significant differences in Hcy, CRP and ESR levels between the two groups before and after treatment (P <0.05). There were significant differences in the levels of Hcy, CRP, ESR and their changes after treatment between the two groups, The treatment group was better than the control group (P <0.05). Conclusion Guizhi Shaoyaozhimu Decoction combined with conventional therapy is effective in treating rheumatoid arthritis, which can significantly relieve the clinical symptoms of patients and improve its homocysteinemia, which may delay rheumatoid arthritis Causes further cardiovascular damage.