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目的:研究分析桂哌齐特治疗急性缺血性脑梗死的临床疗效。方法:将2008年3月-2010年6月临海市第一人民医院诊断明确的152例急性脑梗死患者随机分成治疗组和对照组,每组76例患者,对照组采用急性脑梗死的常规治疗措施,治疗组在对照组常规治疗的基础上给予桂哌齐特注射液320mg+0.9%NaCl 500ml静滴,100ml/h,每日1次。治疗前和治疗后14天进行神经功能缺损、日常生活能力及临床疗效的评定。结果:经14天的治疗后治疗组与对照组的神经功能缺损评分及日常生活能力评分比较有显著的统计学差异(P<0.05);治疗组总有效率为90.79%,对照组总有效率为77.63%,两组相比差异有统计学意义(P<0.05)。结论:桂哌齐特可有效改善急性脑梗死患者的神经功能缺失情况,提高日常生活能力,明显提高临床总有效率,其对急性缺血性脑梗死的疗效肯定,值得临床推广使用。
Objective: To study the clinical efficacy of Cinepazide in the treatment of acute ischemic cerebral infarction. Methods: A total of 152 patients with acute cerebral infarction diagnosed in First People’s Hospital of Linhai from March 2008 to June 2010 were randomly divided into treatment group and control group, with 76 patients in each group. The control group received conventional treatment of acute cerebral infarction Measures, the treatment group in the control group based on the conventional treatment of cinepazide injection 320mg + 0.9% NaCl 500ml intravenous infusion, 100ml / h, 1 times a day. Neurological impairment, daily living ability and clinical efficacy were assessed before treatment and 14 days after treatment. Results: After 14 days of treatment, the neurological deficit scores and daily living ability scores of the treatment group and the control group were significantly different (P <0.05). The total effective rate was 90.79% in the treatment group, and the total effective rate Was 77.63%, the difference between the two groups was statistically significant (P <0.05). Conclusion: Cinepazide can effectively improve the neurological deficits in patients with acute cerebral infarction, improve daily living ability, significantly improve the total effective rate of the clinical efficacy of acute ischemic cerebral infarction, it is worth clinical promotion and use.