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目的探讨围剖宫产术期预防性应用抗菌素的效果。方法选择2006年9月至2007年8月在我院住院行剖宫产的产妇368例,随机分为术前用药组(A组)188例和术后用药组(B组)180例,A组于术前0.5～2小时或麻醉刚开始时静脉滴注头胞噻肟钠4克,持续用药3天;B组于术毕回病房后开始给药,持续用药6～7天。观察两组术后病率、切口感染率及平均住院日。结果A组剖宫产术后病率、切口感染数、平均住院日与B组比较,效果明显优于B组(P<0.01)。结论围剖宫产术期预防性应用抗菌素能有效减少术后切口感染,缩短平均住院日,节约大量医疗费用,值得临床推广应用。
Objective To investigate the effect of prophylactic antibiotics in the cesarean section. Methods 368 pregnant women with cesarean section in our hospital from September 2006 to August 2007 were randomly divided into preoperative medication group (group A) 188 cases and postoperative medication group (group B) 180 cases, A Group 0.5 to 2 hours before surgery or anesthesia at the beginning of intravenous infusion of intravenous cefotaxime sodium 4 grams, continuous medication for 3 days; B group after surgery back to the ward to start administration, continuous medication 6 to 7 days. The postoperative morbidity, incision infection rate and average length of stay were observed. Results The postoperative rates of cesarean section, incisional infection and average length of hospital stay in group A were significantly better than those in group B (P <0.01). Conclusion The cessation of cesarean section prophylactic antibiotics can effectively reduce the incision infection, shorten the average length of stay, save a lot of medical costs, it is worth promoting the clinical application.