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[目的]研究早期宫颈癌患者卵巢移位术后放疗前后卵巢内分泌功能的变化。[方法]55例早期宫颈癌患者行卵巢移位术并且行术后放疗,比较其放疗前、放疗后1个月、3个月、6个月、12个月的血清中卵泡刺激素(FSH)、黄体生成素(LH)和雌二醇(E2)水平,术后随访患者有无围绝经期症状。[结果]卵巢移位术后放疗后1个月、3个月、6个月、12个月的FSH和LH、E2水平与放疗前比较无统计学差异(P>0.05),所有患者术后放疗前及放疗后1个月、3个月、6个月、12个月均未出现围绝经期症状。[结论]术后放疗不会显著性影响患者移位卵巢功能。
[Objective] To study the changes of ovarian endocrine function before and after radiotherapy in patients with early cervical cancer. [Method] Fifty-five patients with early stage cervical cancer underwent ovarian transposition and received postoperative radiotherapy. The levels of FSH in serum of 1 month, 3 months, 6 months and 12 months after radiotherapy were compared. ), Luteinizing hormone (LH) and estradiol (E2). The patients were followed up for climacteric symptoms. [Results] There was no significant difference in FSH, LH and E2 levels at 1 month, 3 months, 6 months and 12 months after radiotherapy in patients with ovarian transposition compared with that before radiotherapy (all P> 0.05) Pre-radiotherapy and radiotherapy 1 month, 3 months, 6 months, 12 months did not appear perimenopausal symptoms. [Conclusion] Postoperative radiotherapy does not significantly affect the patient’s transposition of ovarian function.