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巨细胞病毒单核细胞增多症(Cytomegalovirus mononucleosis)是由巨细胞病毒(CMV)引起的一种单核细胞增多样综合征。本病临床表现与EB病毒(EBV)诱发的传染性单核细胞增多症(IM)很相似,健康成人、儿童及接受输血、器官移植者均可发生。自1965年Klemola首次报道以来,引起人们日益重视。本文拟就有关研究情况作一扼要综述。发病率和感染方式近年来,流行病学和实验研究已证明单核细胞增多样综合征可由多种传染性病原体感染引起,其中90%病例为EBV所致,5~7%为CMV,其次为弓形体、风疹病毒、腺病毒、肝炎病毒等。据统计,IM与本病住院病人比例为13.6∶1。本病在人群中散在发生,以成年人病例
Cytomegalovirus mononucleosis is a mononuclear cell-like syndrome caused by cytomegalovirus (CMV). The clinical manifestations of this disease are very similar to those of Epstein-Barr virus (EBV) -induced infectious mononucleosis (IM). It can occur in healthy adults, children, and those receiving transfusion and organ transplants. Since Klemola first reported in 1965, it has drawn increasing attention. This article intends to give a brief overview of the research situation. Morbidity and Infection In recent years, epidemiological and experimental studies have shown that mononucleosis syndrome can be caused by a variety of infectious agents, of which 90% are EBV, 5-7% are CMV, followed by Toxoplasma, rubella virus, adenovirus, hepatitis virus. According to statistics, IM and inpatient ratio of the disease was 13.6: 1. The disease occurs in the crowd scattered to adult cases