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分子生物学的发展使免疫学从细胞水平进入亚细胞分子水平,开创了分子免疫学的新时期。它的主要标志是:细胞膜研究揭开了艾利希(Ehrlich)“受体学说”(1900)之谜,人们开始认识淋巴细胞表面受体的本质,并从淋巴细胞的膜结构和非膜结构的内部联系,观察和探索到一系列免疫现象的基本规律;应用分子生物学的方法分析免疫球蛋白的结构和免疫球蛋白基因的分子组成,并为免疫反应的分子遗传学研究开辟了途径;从T细胞与B细胞、T细胞与T细胞之间,以及从淋巴细胞和巨噬细胞之间的相互作用中,加深了对免疫调节机制的认识,并为阐明异常免
The development of molecular biology to immunology from the cell level into sub-cellular molecular level, creating a new era of molecular immunology. Its main hallmarks are: Cell membrane research uncovered the mystery of Ehrlich’s “receptor theory” (1900), and people are beginning to recognize the nature of lymphocyte surface receptors and to recognize the membrane structure and non-membrane structure of lymphocytes , Observing and exploring the basic rules of a series of immune phenomena; analyzing the structure of immunoglobulin and the molecular composition of immunoglobulin genes by means of molecular biology, and opening up the way for the study of molecular genetics of immune response; From the interaction between T cells and B cells, T cells and T cells, and from the interaction between lymphocytes and macrophages, understanding of the mechanism of immune regulation is deepened and to elucidate the role of abnormalities