论文部分内容阅读
对正常和慢性感染鼠,经耳廓皮肤分别初次和攻击感染日本血吸虫尾蚴。攻击感染15b后,慢性感染鼠皮肤内的嗜酸粒细胞(EOS)较初次感染鼠明显增加.两组鼠炎症细胞在童虫附近或包围完整及解体的童虫,形成粒细胞性微脓肿。超微结构显示,扁平的EOS紧贴童虫表面,并脱颗粒。粘附处局部皮层可见破坏现象。中性粒细胞(NEU)的粘附不如EOS紧密,未见脱颗粒现象,童虫皮层完整。结果提示,EOS是对日本血吸虫皮肤期童虫有效的杀伤细胞.
In both normal and chronic infected mice, infection of S. japonicum cercaria with initial and challenge via the pinnae skin, respectively. Eosinophils (EOS) in the skin of chronically infected mice were significantly increased after challenge with 15b infection compared with naive mice. Both groups of murine inflammatory cells formed granulocyte-like abscesses around or surrounding the juvenile worms. The ultrastructure shows that the flat EOS sticks to the surface of the wart and degranulates. Adhesion at the local cortical visible destruction. Neutrophil (NEU) adhesion as EOS close, no degranulation, caterpillars intact. The results suggest that EOS is an effective killer cell for Schistosoma japonicum skin-stage schistosomiasis.