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将人肝再生增强因子编码区ｃＤＮＡ亚克隆于表达质粒ｐＢＶ－２２０，构建了高效表达菌株，其特异表达蛋白占细菌可溶性蛋白的２０％，表达产物在体内具有促进肝细胞ＤＮＡ合成和提高ＣＣｌ４致中毒性肝功能衰竭大鼠存活率的作用。
The coding region of human augmenter of liver regeneration was subcloned into the expression plasmid pBV-220 to construct a highly expressed bacterial strain with a specific expression protein of 20% of the bacterial soluble protein. The expression product in vivo enhanced the DNA synthesis of hepatocytes and increased the expression of CCl4 The role of survival rate in toxic liver failure rats.