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本文介绍25例(年龄6～18岁)随访2～103个月(平均26个月)的系统性红斑狼疮性肾炎患者的临床及病理学经验。其中17例为弥漫性增生性肾小球性肾炎,6例为膜性肾病,2例为局灶性肾小球性肾炎。全部弥漫性增生性肾小球性肾炎及局灶性肾小球性肾炎患者均有血尿,但在膜性肾病中仅见到3/6有此变化。10/17例弥漫性增生性肾小球性肾炎及5/6例膜性肾病患者于病程中曾出现肾病综合征。经单用强的松(60毫克/公斤/天)(注:原文如此)或与硫唑嘌呤(2毫克/公斤/天)或环磷酰胺(2毫克/公斤/天)联合应用获得病情缓解。在弥漫性增生性肾小球性肾炎组中22/28例次的复发患者获得临
This article presents the clinical and pathological experience of 25 patients (aged 6-18 years) with systemic lupus erythematosus nephritis who were followed up for 2 to 103 months (mean, 26 months). Of these, 17 were diffuse proliferative glomerulonephritis, 6 were membranous nephropathy and 2 were focal glomerulonephritis. All patients with diffuse proliferative glomerulonephritis and focal glomerulonephritis had hematuria, but only 3/6 of this was seen in membranous nephropathy. 10/17 cases of diffuse proliferative glomerulonephritis and 5/6 cases of membranous nephropathy patients had nephrotic syndrome in the course of the course. Remission was obtained by prednisone alone (60 mg / kg / day) or in combination with azathioprine (2 mg / kg / day) or cyclophosphamide (2 mg / kg / day) . In the diffuse proliferative glomerulonephritis group, 22/28 recurrences were obtained